We stayed here about 5 years ago and it was so nice, we kept it in mind if we were ever staying in Wytheville again. We did just that this year and were so disappointed with how much the motel has gone downhill since our first visit.
Upon getting there, the man working the front desk couldn't find my reservation at first, and had to call someone to help him. He actually kept pulling up reservations for other people with the same first and/or last initial as me--it was as if he's never worked there before. After we were able to finally get into the room, there was an AWFUL smell--maybe ginger or celery--that permeated everything.
I also noticed that there were quite a few people in rooms, but only one car in the lot. There were a handful of cars coming in and out, and it didn't make us feel particularly safe.
I was woken up in the middle of the night to a new smell, as someone was smoking pot right outside of our door and yelling into the room next to us. Additionally, the owners appear to live on-site and were having a loud party (at least it sounded like that), leaving me with a terrible attempt at sleeping.
We were supposed to stay at the Travel Lite again on our way back from vacation, but cancelled the return trip reservation as soon as we checked out of our first stay. I would recommend looking elsewhere in Wytheville for a hotel--we found a great place for only $9 more.